Dab tsi yogMelatonin Bulk Hmoov Hmoov?
Chemically hu ua n {- acetyl-5-metoxytryptamine (CAS: 73-31-4),Melatonin Bulk Hmoov HmoovYog qhov siab - purity, dawb crystalline hmoov feem ntau siv los ntawm cov neeg siv khoom noj khoom haus, nutraceutical, thiab xws li compound tshuaj tsev muag tshuaj lag luam. Cov hluavtaws no yuav tsum tsim cov tuam txhab los tsim cov qauv tshwj xeeb rau kev saib xyuas ntawm cov txheej txheem ntuj ntawm cov txheej txheem so thiab repose los ntawm lub cev. Bulk hmoov daim ntawv tso cai rau txoj kev ywj pheej tshaj plaws ntawm cov khoom lag luam, ntsiav tshuaj, cov kua nyeem kua, chewab, thiab ua kom sib xyaw ua ke. Qhov tseeb tias nws yog ib qho hmoov zoo yog tsim nyog nyob rau hauv cov nqe lus ntawm kev sib xyaw ua ke los ntawm loj txheej txheem sib xyaw thiab cov txheej txheem kev lag luam ntau, cia kev tswj hwm ntawm kev tswj hwm thiab kev sib txawv ntawm cov pob. Nws yog siv los tsim cov tsim khoom tsim khoom-}}} pahuv, thiab botanicals, los txhim kho tus neeg {{8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8} {8}! Ua ib qho tseem ceeb ua ke, ib qho khoom noj khoom siv sib xws thiab pom zoo yuav yog qhov tseem ceeb rau kev ua lag luam thiab cov khoom lag luam uas tsis muaj kev cuam tshuam.
Coa
| Yam | Kev qhia tshwj xeeb | Qho kawg | Txoj kev xeem |
| Kev tshwm sim | Dawb rau tawm -} e} crystalline hmoov | Ntuas | Ntawm kev pom |
| Tus ntxhiab | Tus yam ntxwv | Ntuas | Xwm txheej |
| Assay (purity) | Ntau dua los yog sib npaug rau 98.0% | 98.60% | HPLC |
| Daim qhia npe | Yam zoo | Yam zoo | HPLC / IR |
| Poob rau ziab | Tsawg dua los yog sib npaug rau 0.5% | 0.18% | USP<731> |
| Residue ntawm ignition | Tsawg dua los yog sib npaug rau 0.1% | 0.05% | USP<281> |
| Cov hlau hnyav (PB, raws li, CD, HG) | Tsawg dua los yog sib npaug rau 10 ppm | < 10 ppm | ICP - ms |
| Txhuas (PB) | Tsawg dua los yog sib npaug rau 3 ppm | 0.52 ppm | ICP - ms |
| Arsenic (raws li) | Tsawg dua los yog sib npaug rau 2 ppm | 0.21 ppm | ICP - ms |
| Cadmium (CD) | Tsawg dua los yog sib npaug rau 1 ppm | 0.05 ppm | ICP - ms |
| Mercury (Hg) | Tsawg dua los yog sib npaug rau 0.1 ppm | Nd | ICP - ms |
| Residual cov kuab tshuaj | Ntsib USP<467> | Ntuas | Gc |
| Qhov loj me me | 100% pass 80 mesh | Ntuas | Sab cib xeem |
| Ceev ntom | 0.40 - 0.60 g / ml | 0.48 g / ml | USP Txuj Ci |
| Tapped ntom | 0.60 - 0.80 g / ml | 0.72 g / ml | USP Txuj Ci |
| Microbiological Testions | |||
| Tag Nrho Cov Phaj Suav | Tsawg dua los yog sib npaug rau 1,000 cfu / g | < 100 CFU/g | USP<2021> |
| Poov koob & pwm | Tsawg dua los yog sib npaug rau 100 cfu / g | < 10 CFU/g | USP<2021> |
| E. coli | Tsis zoo | Tsis zoo | USP<2022> |
| Tus ntses siav | Tsis zoo | Tsis zoo | USP<2022> |
Koj puas xav nyob hauv peb cov khoom? TsuasTso lus ciaNtawm nplooj ntawv no lossisTiv Tauj Peb ncaj qhaTxhawm rau kom tau txais cov qauv dawb thiab kev txhawb nqa tshaj plaws!
Mechanism ntawm Kev Ua
Qhov kev txiav txim hom ntawmMelatonin Hmoov, N {- acetyl-5-methoxyinptamine, tsuas yog ob txoj kev sib txawv, uas ua rau nws ua molecule ntawm kev siv ntawm ntau yam khoom.
Nws lub ntsiab mechanism cuam tshuam nrog kev muaj peev xwm ua tau li ntawm kev ua siab ntev, next} Coion {1}. Cov receptors no tau pom nyob rau hauv yuav luag txhua cov ntaub so ntswg, thiab lawv yog feem ntau ntawm gi / o protein. Kev tsim txom ntawm MT1 thiab MT2 ua rau cov kab mob hlwb rau inhibit adenylyl cyclase, uas lowters cov qib ntawm cyclic amp (chaw pw hav zoov (chaw pw hav zoov (chaw pw hav zoov. Qhov kev hloov pauv no ua lub luag haujlwm tseem ceeb hauv kev tswj hwm ntawm qib cellular, xws li hauv kev sib dhos ntawm kev ua phooj ywg thiab lwm cov txheej txheem hauv lub cev.
Nws cov haujlwm tseem ceeb thib ob yog qhov muaj zog tsis yog}}}}}}}} antioxidant uas muaj txiaj ntsig zoo. Nws yog cov lipophilic zoo li lipophilic thiab xws li, nws tuaj yeem nkag rau tag nrho cov kev sib tw ntawm cov cell, xws li Mitochondria. Nws yog lub zog scavenger ntawm ib tug xov tooj ntawm reactive oxygen hom (Ros) thiab reactive nitrogen hom (rns). Ntxiv mus, nws nce lub cev tiv thaiv kab mob cellular Qhov no ua raws li {{- txog ntawm kev nqis tes ua, piv txwv li, lub pleiotropic dawb rau cov khoom siv ntau dua hauv cov qauv zoo dua.
Kev ua
1. Pib khoom siv hluavtaws / acylation:
Cov txheej txheem feem ntau pib nrog tryptamine lossis 5 - metoxytryptamine. Qhov tseem ceeb tshaj plaws yog qhov ua rau cov amline pawg (n {
2. Methoxylation / Methylation:
Yog tias yog cov txheej txheem ua ntej tsis tau methoxylated, ib qho tshuaj methylation tseem ceeb heev. Qhov tshuaj tiv thaiv no cuam tshuam rau methylating tus neeg sawv cev rau cov pab pawg methoxy (}}}
3. Cov tshuaj tiv thaiv kab & kev sib cais:
Tom qab synthesis ua tiav, cov tshuaj tiv thaiv yog qhov zoo quenched rau deenenivate lub resagents reagents thiab nres cov tshuaj lom neeg. Cov khoom lag luam melatonin no yog qhov feem ntau tau zoo tu los ntawm kev daws los ntawm kev tswj hwm los ntawm kev kub ntxhov raws li kub lossis kub sib tov.
4. Kev ua kom huv (crystallization):
Qhov no yog ib kauj ruam tseem ceeb heev rau kev muaj lub siab tu siab xav tau los ua kev muag khoom ntau. Cov khoom nyoos yog yaj thiab recrystallized nyob rau hauv kev ntxub ntxaug thiab kev ntxub ntxaug. Qhov no ua rau cov ntshiab melatonin xaiv kom crystallize tawm, tawm hauv feem ntau cov tshuaj cawv hauv leej niam cawv.
5. Kom qhuav thiab milling:
Lub muaju yog kev ua kom huv, thiab cov txheej txheem ntawm kev lim dej kom tshem tawm txhua qhov kev txiav txim siab kom tshem tawm txhua qhov kev txiav txim siab kom tshem tau txhua qhov kev ua raws li cov qauv kev nyab xeeb. Cov khoom lag luam yog tom qab ntawd feem ntau yog milled (micronized) los muab cov nplua, cov me me kom muaj kev sib xyaw ua ke hauv cov khoom lag luam tiav kawg.
6. Tswjhwm Zoo & Ntim:
Tiav lawmCov ntshiab ntau melatoninyog tom qab ntawd raug rau cov kev ntsuam xyuas dav dav raws li CGMP cov kev xav tau. Kev xeem yuav suav nrog kev kuaj xyuas cov cim, kev ua qias tuaj 98% thiab cov hlau hnyav, cov kab mob microbants txwv. Tom qab tau txais ntawv pov thawj los ntawm daim ntawv pov thawj kev tsom xam (COA), cov khoom kawg tau ntim rau hauv cov ntim ntau, xws li ,. Nyob rau hauv 25 kg fiber ntau nruas, kom tau faib.
Haum rau
1. Tus neeg laus ua haujlwm -} cov neeg muaj hnub nyoog:
Ua qhov cuam tshuam loj tshaj plaws los ntawm kev ua neej - Cov sijhawm ua haujlwm pw tsaug zog, thiab ntau dua cov khoom siv ua haujlwm, thiab ntau lub sijhawm ua haujlwm xav tau siab ntawm qhov yooj yim ntawmMelatonin ntxivDosage cov ntawv, xws li nrawm -}}} pa tshuaj, cov pos hniav, kom pab tau cov kua rau yav dhau los.
2. Cov neeg taug kev thiab cov neeg ua haujlwm hloov chaw:
Cov neeg no xav tau cov txuj ci tshwj xeeb kom kov yeej cov teeb meem ib ntus Tam sim no - tso thiab tswj - tso tawm thev naus laus zis los ntawm cov chaw tsim khoom no.
3. Cov neeg siv laus (cov neeg siv khoom siv geriatric):
Nov yog cov pej xeem hauv ntiaj teb, uas xav tau cov kev daws teeb meem zoo rau lub sijhawm lawv hloov siab. Cov khoom lag luam uas tau ua tiav cov hom ntu no feem ntau yog raws cov kev yooj yim rau kev noj, thiab cov chosage, nrog rau kev nyiam thiab muaj txiaj ntsig zoo.
4. Cov kev noj qab haus huv thiab kev ua lag luam ua haujlwm:
Qhov no yog lub nrawm nrawm - loj zuj zus los cuam tshuam nrog cov neeg siv khoom uas xav ntxiv qee cov khoom noj khoom haus ntxiv rau lawv cov zaub mov txhua hnub. Cov tuam txhab tsim, nyob rau hauv cov ntaub ntawv, nyob rau hauv cov ntaub ntawv no, muab cov ntaub ntawv los sib zog ua haujlwm, nrog rau kev sib xyaw ua ke xws li} tus txiv neej thiab magnesium.
Ntawv muaj
Miskas Warehouse
Kev nthuav tawm
Cim npe nrov: Melatonin co hmoov, Melatonin hmoov ntau, cov chaw tsim khoom, cov khoom lag luam, khoom siv, kosher, ISO, HACCP
