Synthetic astaxanthin thiabntuj astaxanthinqhov tseem ceeb sib txawv; lawv lub peev xwm antioxidant, cov ntsiab lus, thiab purity tsis zoo ib yam. Lawv txawv hauv cov qauv. Yog li ntawd, muaj qhov sib txawv ntawm nws qhov ua tau zoo thiab lub luag haujlwm ntawm nws.
Nws yog tsim nyob rau hauv ob txoj kev: dag synthesis thiab biological acquisition. Artificial synthesis yog ib txoj kev tshuaj kom tau los ntawm carotene; Kev noj zaub mov zoo feem ntau muaj peb qhov chaw lom neeg: pov tseg los ntawm cov khoom lag luam hauv dej ua lag luam, Phaffia rhodozyma, thiab microalgae (Feem ntau Haematococcus Pluvialis).
Nws yog tsim nyob rau hauv ob txoj kev: dag synthesis thiab biological acquisition. Synthetic tsis tsuas yog kim tab sis kuj tseem txawv ntawm cov xwm ntawm cov qauv, kev ua haujlwm, kev siv, thiab kev nyab xeeb.
Raws li cov qauv:
Vim yog kev ua haujlwm ntawm qhov muag pom ntawm hydroxyl pawg (-oh) ntawm ob qhov kawg, nws muaj peb isomers: 3s-3's, 3r-3's, 3r-3'r (kuj hu ua levorotatory, racemic, dextrorotatory) Hom, nyob rau hauv uas hluavtaws yog ib tug sib tov ntawm 3 hom qauv (25 feem pua sab laug-tes, 25 feem pua txoj cai, thiab txog 50 feem pua ntawm haiv neeg), nrog rau cov tshuaj tua kab mob me me, cov poov xab muab tau nws. yog 100 feem pua dextrorotatory (3r-3'r) thiab muaj ib feem ntawm cov tshuaj antioxidant; cov saum toj no ob qhov chaw uas yog tsuas yog siv nyob rau hauv cov xim ntawm cov tsiaj tsis noj thiab cov ntaub ntawv. Tsuas yog algae-derived, uas muaj 100 feem pua levorotatory (3s-3's) cov qauv thiab muaj cov khoom siv roj ntsha muaj zog tshaj plaws.
Cov tshuaj synthesis yuav inevitably qhia cov tshuaj impurity, xws li cov khoom uas tsis yog natural by-products generated thaum lub synthesis txheej txheem, uas yuav txo tau nws bioavailability kev nyab xeeb. Nrog rau qhov nce ntawm qhov xwm txheej, kev tswj cov tshuaj sib xyaw ua ke tau dhau los ua nruj dua hauv cov tebchaws thoob ntiaj teb. Piv txwv li, US Food and Drug Administration (FDA) tau txwv tsis pub siv tshuaj lom neeg los ntawm kev nkag mus rau cov khoom noj thiab cov khoom noj khoom haus (Supplements), thiab ntuj tau txais daim ntawv pov thawj kev nyab xeeb (GRAS) hauv FDA. Nws tuaj yeem raug cai nkag mus rau cov khoom noj thiab cov khoom noj khoom haus ntxiv. Nws cov khoom lag luam feem ntau nyiam tsim cov khoom siv roj ntsha ntawm cov xwm txheej thiab yog li tsim nws ntawm qhov loj.
Ntau qhov chaw ntawm astaxanthin muaj lwm cov qauv tshuaj thiab ntau yam antioxidant muaj peev xwm. Thiab astaxanthin lub zog muaj zog antioxidant muaj peev xwm cuam tshuam los ntawm nws cov qauv tsim tshwj xeeb. Cov astaxanthin muab rho tawm los ntawm Haematococcus Pluvialis muaj 100 feem pua ntawm cov qauv levorotatory, nrog super-muaj zog antioxidant muaj peev xwm, thiab nws cov kev ua haujlwm lom neeg kuj muaj zog heev. Phaffia-derived astaxanthin muaj 100 feem pua txoj cai sab xis. Nws lub peev xwm antioxidant yog thib ob; nws yog muab rho tawm los ntawm ntses, cws, crabs, thiab lwm yam tsiaj thiab yog ib tug sib tov ntawm peb hom. Lub zog antioxidant yog thib ob, thiab qhov kawg yog cov khoom siv dag zog. Astaxanthin yog 100 feem pua ntawm cov qauv racemic, tsis muaj cov tshuaj tua kab mob antioxidant, thiab tsis muaj kev ua haujlwm lom neeg uas astaxanthin yuav tsum muaj, yog li nws tsuas yog siv tau los ua tshuaj zas xim.
Yog li ntawd,ntuj astaxanthinyog superior rau hluavtaws astaxanthin nyob rau hauv cov qauv, physiological muaj nuj nqi, daim ntawv thov nyhuv, thiab kev nyab xeeb.
